Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma

Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma

Background: Head and neck squamous cell carcinoma (HNSCC) displays a large heterogeneity in treatment response, and consequently in patient prognosis. Despite extensive efforts, no clinically validated model is available to predict tumor response. Here we describe a functional test for predicting tu...

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Bibliographic Details
Main Authors: Marta E. Capala, Katrin S. Pachler, Iris Lauwers, Maarten A. de Korte, Nicole S. Verkaik, Hetty Mast, Brend P. Jonker, Aniel Sewnaik, Jose A. Hardillo, Stijn Keereweer, Dominiek Monserez, Senada Koljenovic, Bianca Mostert, Gerda M. Verduijn, Steven Petit, Dik C. van Gent
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
HNSCC
radiotherapy
cisplatin
predictive model
organotypic tumor slices
ex vivo
Online Access:https://www.mdpi.com/2072-6694/15/2/478

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https://www.mdpi.com/2072-6694/15/2/478

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