Endoplasmic Reticulum Stress and Neurodegeneration in Experimental Cerebral Malaria

Endoplasmic Reticulum Stress and Neurodegeneration in Experimental Cerebral Malaria

Experimental cerebral malaria (ECM) resulting from Plasmodium berghei ANKA (PbA) infection in mice results in neuronal cell death. However, the precise mechanisms leading to neuronal cell death in ECM have not been fully elucidated. In the present study, we report the presence of endoplasmic reticul...

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Bibliographic Details
Main Authors: Sripada Santosh Anand, Phanithi Prakash Babu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2012-05-01
Series:Neurosignals
Subjects:
C/EBP homologous protein (CHOP)
Fluoro-Jade B stain
Cerebral malaria
Neuronal cell death
Protein kinase RNA-like endoplasmic reticulum kinase
Phosphorylated eukaryotic initiation factor α
Activating transcription factor 4
Caspase-12
Binding immunoglobulin protein
Online Access:http://www.karger.com/Article/FullText/336970

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http://www.karger.com/Article/FullText/336970

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