LRP6 Is a Functional Receptor for Attenuated Canine Distemper Virus

LRP6 Is a Functional Receptor for Attenuated Canine Distemper Virus

ABSTRACT Wild-type canine distemper virus (CDV) is an important pathogen of dogs as well as wildlife that can infect immune and epithelial cells through two known receptors: the signaling lymphocytic activation molecule (SLAM) and nectin-4, respectively. Conversely, the ferret and egg-adapted CDV-On...

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Bibliographic Details
Main Authors: Vaiva Gradauskaite, Marine Inglebert, John Doench, Melanie Scherer, Martina Dettwiler, Marianne Wyss, Neeta Shrestha, Sven Rottenberg, Philippe Plattet
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:mBio
Subjects:
attenuated CDV
CRISPR/Cas9 KO screen
LRP6
cell entry
receptor
Online Access:https://journals.asm.org/doi/10.1128/mbio.03114-22

Internet

https://journals.asm.org/doi/10.1128/mbio.03114-22

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