Incidence, risk factors and outcomes of checkpoint inhibitor-induced liver injury: A 10-year real-world retrospective cohort study

Incidence, risk factors and outcomes of checkpoint inhibitor-induced liver injury: A 10-year real-world retrospective cohort study

Background & Aims: Checkpoint inhibitors (CPI) account for increasing numbers of drug-induced liver injury (DILI) cases. We aimed to determine the incidence rate and risk factors associated with checkpoint inhibitor-induced liver injury (ChILI). Methods: Prescription event monitoring was per...

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Bibliographic Details
Main Authors: Edmond Atallah, Sarah J. Welsh, Brent O’Carrigan, Ana Oshaughnessy, Igboin Dolapo, Andrew S. Kerr, Joanna Kucharczak, Colin Y.C. Lee, Colin Crooks, Amy Hicks, Chenchu Ramu Chimakurthi, Ankit Rao, Hester Franks, Poulam M. Patel, Guruprasad P. Aithal
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:JHEP Reports
Subjects:
Checkpoint inhibitors
Immunotherapy
Immune-mediated hepatitis
Hepatotoxicity
Drug-induced liver injury
Incidence rate
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923001829

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http://www.sciencedirect.com/science/article/pii/S2589555923001829

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