N-wasp is required for structural integrity of the blood-testis barrier.

During spermatogenesis, the blood-testis barrier (BTB) segregates the adluminal (apical) and basal compartments in the seminiferous epithelium, thereby creating a privileged adluminal environment that allows post-meiotic spermatid development to proceed without interference of the host immune system...

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Bibliographic Details
Main Authors: Xiang Xiao, Dolores D Mruk, Elizabeth I Tang, R'ada Massarwa, Ka Wai Mok, Nan Li, Chris K C Wong, Will M Lee, Scott B Snapper, Ben-Zion Shilo, Eyal D Schejter, C Yan Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4072540?pdf=render