Genomic profiling of messenger RNAs and microRNAs reveals potential mechanisms of TWEAK-induced skeletal muscle wasting in mice.

Skeletal muscle wasting is a devastating complication of several physiological and pathophysiological conditions. Inflammatory cytokines play an important role in the loss of skeletal muscle mass in various chronic diseases. We have recently reported that proinflammatory cytokine TWEAK is a major mu...

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Bibliographic Details
Main Authors: Siva K Panguluri, Shephali Bhatnagar, Akhilesh Kumar, John J McCarthy, Apurva K Srivastava, Nigel G Cooper, Robert F Lundy, Ashok Kumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2808241?pdf=render