Exploring the neuroprotective potential of Nrf2-pathway activators against annonacin toxicity
Abstract Modulation of the Nrf2 pathway, a master regulator of the antioxidant response and cellular metabolism, has been suggested as a promising therapeutic strategy in tauopathies, a heterogeneous group of neurodegenerative disorders characterized by intracellular proteinaceous inclusions of abno...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-70837-1 |