Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer
Summary: Pancreatic ductal adenocarcinoma (PDAC) exhibits an immunosuppressive tumor microenvironment (TME) contributing to its therapeutic resistance. Following our previous studies, we report that mast cells infiltrating the PDAC TME foster this immunosuppression and desmoplasia. Mast cell infiltr...
| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado: |
Elsevier
2024-11-01
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| Series: | iScience |
| Subjects: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2589004224023101 |