Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Summary: Pancreatic ductal adenocarcinoma (PDAC) exhibits an immunosuppressive tumor microenvironment (TME) contributing to its therapeutic resistance. Following our previous studies, we report that mast cells infiltrating the PDAC TME foster this immunosuppression and desmoplasia. Mast cell infiltr...

Descripció completa

Dades bibliogràfiques
Autors principals: Ying Ma, Xiangqin Zhao, Jingyan Feng, Suimin Qiu, Baoan Ji, Lu Huang, Patrick Hwu, Craig D. Logsdon, Huamin Wang
Format: Article
Idioma:English
Publicat: Elsevier 2024-11-01
Col·lecció:iScience
Matèries:
Molecular biology
Neuroscience
Immunology
Cancer
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2589004224023101

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224023101

Ítems similars