Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Summary: Pancreatic ductal adenocarcinoma (PDAC) exhibits an immunosuppressive tumor microenvironment (TME) contributing to its therapeutic resistance. Following our previous studies, we report that mast cells infiltrating the PDAC TME foster this immunosuppression and desmoplasia. Mast cell infiltr...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Ying Ma, Xiangqin Zhao, Jingyan Feng, Suimin Qiu, Baoan Ji, Lu Huang, Patrick Hwu, Craig D. Logsdon, Huamin Wang
Format: Artykuł
Język:English
Wydane: Elsevier 2024-11-01
Seria:iScience
Hasła przedmiotowe:
Molecular biology
Neuroscience
Immunology
Cancer
Dostęp online:http://www.sciencedirect.com/science/article/pii/S2589004224023101

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224023101

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