Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Summary: Pancreatic ductal adenocarcinoma (PDAC) exhibits an immunosuppressive tumor microenvironment (TME) contributing to its therapeutic resistance. Following our previous studies, we report that mast cells infiltrating the PDAC TME foster this immunosuppression and desmoplasia. Mast cell infiltr...

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Detalhes bibliográficos
Principais autores: Ying Ma, Xiangqin Zhao, Jingyan Feng, Suimin Qiu, Baoan Ji, Lu Huang, Patrick Hwu, Craig D. Logsdon, Huamin Wang
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2024-11-01
coleção:iScience
Assuntos:
Molecular biology
Neuroscience
Immunology
Cancer
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004224023101

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224023101

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