Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Tumor-infiltrating mast cells confer resistance to immunotherapy in pancreatic cancer

Summary: Pancreatic ductal adenocarcinoma (PDAC) exhibits an immunosuppressive tumor microenvironment (TME) contributing to its therapeutic resistance. Following our previous studies, we report that mast cells infiltrating the PDAC TME foster this immunosuppression and desmoplasia. Mast cell infiltr...

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Bibliografiska uppgifter
Huvudupphovsmän: Ying Ma, Xiangqin Zhao, Jingyan Feng, Suimin Qiu, Baoan Ji, Lu Huang, Patrick Hwu, Craig D. Logsdon, Huamin Wang
Materialtyp: Artikel
Språk:English
Publicerad: Elsevier 2024-11-01
Serie:iScience
Ämnen:
Molecular biology
Neuroscience
Immunology
Cancer
Länkar:http://www.sciencedirect.com/science/article/pii/S2589004224023101

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224023101

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