Phosphorylation of MIF by PIP4K2a is necessary for cilia biogenesis

Abstract Primary cilia are microtubule-based organelles that play important roles in development and tissue homeostasis. Macrophage migration inhibitory factor (MIF) has long been recognized as a secreted cytokine in the pathogenesis of various human diseases, including cancer and autosomal dominant...

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Bibliographic Details
Main Authors: Lu Zhang, Hongbing Zhang, Ewud Agborbesong, Julie Xia Zhou, Xiaogang Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06323-9