H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation.

H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation.

The histone H2A variant H2A.Z is essential for embryonic development and for proper control of developmental gene expression programs in embryonic stem cells (ESCs). Divergent regions of amino acid sequence of H2A.Z likely determine its functional specialization compared to core histone H2A. For exa...

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Bibliographic Details
Main Authors: Vidya Subramanian, Aprotim Mazumder, Lauren E Surface, Vincent L Butty, Paul A Fields, Allison Alwan, Lillian Torrey, Kevin K Thai, Stuart S Levine, Mark Bathe, Laurie A Boyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3749939?pdf=render

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http://europepmc.org/articles/PMC3749939?pdf=render

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