The Roles of S100A4 and the EGF/EGFR Signaling Axis in Pulmonary Hypertension with Right Ventricular Hypertrophy

The Roles of S100A4 and the EGF/EGFR Signaling Axis in Pulmonary Hypertension with Right Ventricular Hypertrophy

Pulmonary hypertension (PH) is characterized by increased pulmonary arterial pressure caused by the accumulation of mesenchymal-like cells in the pulmonary vasculature. PH can lead to right ventricular hypertrophy (RVH) and, ultimately, heart failure and death. In PH etiology, endothelial-to-mesench...

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Bibliographic Details
Main Authors: Maria Laggner, Philipp Hacker, Felicitas Oberndorfer, Jonas Bauer, Thomas Raunegger, Christian Gerges, Tamás Szerafin, Jürgen Thanner, Irene Lang, Nika Skoro-Sajer, Hendrik Jan Ankersmit, Bernhard Moser
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biology
Subjects:
pulmonary hypertension
chronic thromboembolic pulmonary hypertension
idiopathic pulmonary arterial hypertension
S100A4
epidermal growth factor
epidermal growth factor receptor
Online Access:https://www.mdpi.com/2079-7737/11/1/118

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https://www.mdpi.com/2079-7737/11/1/118

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