Sex-Differences in Aortic Stenosis: Mechanistic Insights and Clinical Implications

Sex-Differences in Aortic Stenosis: Mechanistic Insights and Clinical Implications

ObjectiveWe aim to analyse sex-specific differences in aortic valves (AVs) and valve interstitial cells (VICs) from aortic stenosis (AS) patients.Approach and Results238 patients with severe AS undergoing surgical valve replacement were recruited. Two hundred and two AVs (39.1% women) were used for...

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Bibliographic Details
Main Authors: Lara Matilla, Mattie Garaikoetxea, Vanessa Arrieta, Amaia García-Peña, Amaya Fernández-Celis, Adela Navarro, Alicia Gainza, Virginia Álvarez, Rafael Sádaba, Eva Jover, Natalia López-Andrés
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aortic stenosis
sex
valve interstitial cells
extracellular matrix
remodeling
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.818371/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.818371/full

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