Anti-Tuberculosis Mur Inhibitors: Structural Insights and the Way Ahead for Development of Novel Agents

Mur enzymes serve as critical molecular devices for the synthesis of UDP-MurNAc-pentapeptide, the main building block of bacterial peptidoglycan polymer. These enzymes have been extensively studied for bacterial pathogens such as <i>Escherichia coli</i> and <i>Staphylococcus aureus...

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Bibliographic Details
Main Authors: Kunal Mehta, Mihir Khambete, Arundhati Abhyankar, Abdelwahab Omri
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/3/377