Physiological and pathophysiological aspects of blood platelet activation through CLEC-2 receptor

Platelet activating receptor CLEC-2 has been identified on platelet surface a decade ago. The only confirmed endogenous CLEC-2 agonist is podoplanin. Podoplanin is a transmembrane protein expressed by lymphatic endothelial cells, reticular fibroblastic cells in lymph nodes, kidney podocytes and by c...

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Bibliographic Details
Main Authors: A. A. Martyanov, V. N. Kaneva, M. A. Panteleev, A. N. Sveshnikova
Format: Article
Language:Russian
Published: ABV-press 2018-10-01
Series:Онкогематология
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/310