Established thymic epithelial progenitor/stem cell-like cell lines differentiate into mature thymic epithelial cells and support T cell development.

Common thymic epithelial progenitor/stem cells (TEPCs) differentiate into cortical and medullary thymic epithelial cells (TECs), which are required for the development and selection of thymocytes. Mature TEC lines have been widely established. However, the establishment of TEPC lines is rarely repor...

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Bibliographic Details
Main Authors: Pengfei Chen, Jun Zhang, Yu Zhan, Juanjuan Su, Yarui Du, Guoliang Xu, Yufang Shi, Ulrich Siebenlist, Xiaoren Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781041?pdf=render