Frequency of BRCA1 and BRCA2 mutations in ovarian cancer patients in South-East Poland

Frequency of BRCA1 and BRCA2 mutations in ovarian cancer patients in South-East Poland

Abstract Background Mutations in BRCA1 and BRCA2 genes are well-established risk factors of breast and ovarian cancer. In our former study, we observed that approximately 6% of unselected ovarian cancer patients in the region of Podkarpacie (South-East Poland) carry BRCA1 causative founder variants,...

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Bibliographic Details
Main Authors: Andrzej Jasiewicz, Helena Rudnicka, Wojciech Kluźniak, Wojciech Gronwald, Tomasz Kluz, Cezary Cybulski, Anna Jakubowska, Jan Lubiński, Jacek Gronwald
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
BRCA1 and BRCA2 mutation
Ovarian cancer
Poland
Online Access:https://doi.org/10.1186/s13053-022-00219-z

Internet

https://doi.org/10.1186/s13053-022-00219-z

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