Amyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS development.

Amyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS development.

Genetic and biochemical mechanisms linking onset or progression of Alzheimer Disease and prion diseases have been lacking and/or controversial, and their etiologies are often considered independent. Here we document a novel, conserved and specific genetic interaction between the proteins that underl...

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Bibliographic Details
Main Authors: Darcy M Kaiser, Moulinath Acharya, Patricia L A Leighton, Hao Wang, Nathalie Daude, Serene Wohlgemuth, Beipei Shi, W Ted Allison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517466?pdf=render

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http://europepmc.org/articles/PMC3517466?pdf=render

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