Aberrant Expression of Rb and pRb-780, pRb-795 in Lung Adenocarcinoma Patients with EGFR Mutations and Their Clinical Significance

Aberrant Expression of Rb and pRb-780, pRb-795 in Lung Adenocarcinoma Patients with EGFR Mutations and Their Clinical Significance

Background and objective Rb is an important tumor suppressor gene that regulates cell cycle progression. Rb dysfunction can lead to over proliferation of cells and lead to the occurrence of tumor. Loss or reduced Rb expression as well as over phosphorylation of Rb are important mechanisms of Rb dysf...

Full description

Bibliographic Details
Main Authors: Yunlong DONG, Minghui LIU, Yongwen LI, Ying LI, Chenlong ZHAO, Yin YUAN, Hui DU, Zihe ZHANG, Hongbing ZHANG, Hongyu LIU, Jun CHEN
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2017-05-01
Series:Chinese Journal of Lung Cancer
Subjects:
Lung neoplasms
Rb
pRb-780
pRb-795
EGFR
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2017.05.03

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2017.05.03

Similar Items