Intratumoral CXCR4hi neutrophils display ferroptotic and immunosuppressive signatures in hepatoblastoma

Intratumoral CXCR4hi neutrophils display ferroptotic and immunosuppressive signatures in hepatoblastoma

Pediatric hepatoblastoma (HB) is the most common primary liver malignancy in infants and children. With great diversity and plasticity, tumor-infiltrating neutrophils were one of the most determining factors for poor prognosis in many malignant tumors. In this study, through bulk RNA sequencing for...

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Bibliographic Details
Main Authors: Zhengjing Lu, Xiaolin Wang, Jun Feng, Wenjia Chai, Wei Wang, Qixin Wang, Shen Yang, Wei Yang, Yan Su, Wenjun Mou, Yun Peng, Huanmin Wang, Jingang Gui
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
neutrophil
ferroptosis
immunosuppression
hepatoblastoma
CXCR4
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1363454/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1363454/full

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