LKB1 Regulates Mitochondria-Dependent Presynaptic Calcium Clearance and Neurotransmitter Release Properties at Excitatory Synapses along Cortical Axons.

LKB1 Regulates Mitochondria-Dependent Presynaptic Calcium Clearance and Neurotransmitter Release Properties at Excitatory Synapses along Cortical Axons.

Individual synapses vary significantly in their neurotransmitter release properties, which underlie complex information processing in neural circuits. Presynaptic Ca2+ homeostasis plays a critical role in specifying neurotransmitter release properties, but the mechanisms regulating synapse-specific...

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Bibliographic Details
Main Authors: Seok-Kyu Kwon, Richard Sando, Tommy L Lewis, Yusuke Hirabayashi, Anton Maximov, Franck Polleux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4948842?pdf=render

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http://europepmc.org/articles/PMC4948842?pdf=render

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