Natural spike trains trigger short- and long-lasting dynamics at hippocampal mossy fiber synapses in rodents.

Synapses exhibit strikingly different forms of plasticity over a wide range of time scales, from milliseconds to hours. Studies on synaptic plasticity typically use constant-frequency stimulation to activate synapses, whereas in vivo activity of neurons is irregular.Using extracellular and whole-cel...

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Bibliographic Details
Main Authors: Anja Gundlfinger, Jörg Breustedt, David Sullivan, Dietmar Schmitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2848597?pdf=render