Analysis of morphological and neurochemical changes in subthalamic nucleus neurons in response to a unilateral 6-OHDA lesion of the substantia nigra in adult rats

Analysis of morphological and neurochemical changes in subthalamic nucleus neurons in response to a unilateral 6-OHDA lesion of the substantia nigra in adult rats

Background: Subthalamic nucleus (STN) neurons undergo changes in their pattern of activity and morphology during the clinical course of Parkinson’s disease (PD). Striatal dopamine depletion and hyperactivity of neurons in the parafascicular nucleus (Pf) of the intralaminar thalamus are predicted to...

Full description

Bibliographic Details
Main Authors: Katayoun Sedaghat, Andrew L. Gundlach, David I. Finkelstein
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:IBRO Neuroscience Reports
Subjects:
Parafascicular nucleus
Parkinson’s disease
Substantia nigra pars compacta (SNpc)
Subthalamic nucleus
Tyrosine hydroxylase (TH)
Vesicular glutamate transporter-2 (vGlut2)
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242121000038

Internet

http://www.sciencedirect.com/science/article/pii/S2667242121000038

Similar Items