Roles of alpha-7 nicotinic acetylcholine receptors and spleen in the lung injury induced by a repeated saline lavage in rat

Roles of alpha-7 nicotinic acetylcholine receptors and spleen in the lung injury induced by a repeated saline lavage in rat

Abstract Background The study aimed to determine whether or notα7 nicotinic acetylcholine receptors (α7nAChR) induce anti-inflammatory effects directly in the lung or through the spleen pathway in a sterile model of lung injury by saline lavage. Methods Male Sprague Dawley rats were divided into sev...

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Bibliographic Details
Main Authors: Hossein Fatemikia, Amirreza Dehghanian, Bizhan Ziaian, Maryam Farokhipour, Farzaneh Ketabchi
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Pulmonary Medicine
Subjects:
α7nAChR
Lung
Nicotine
MLA
Saline lavage
Spleen
Online Access:https://doi.org/10.1186/s12890-022-02151-3

Internet

https://doi.org/10.1186/s12890-022-02151-3

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