Mammalian expression of virus-like particles for advanced mimicry of authentic influenza virus.

BACKGROUND: Influenza A viruses are major human and animal pathogens with huge economic and societal impact from illness, hospitalizations, and deaths. Virus-like particles (VLPs) of influenza virus have been suggested as a vaccine candidate offering improved safety and efficacy. To develop this con...

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Bibliographic Details
Main Authors: Chia-Ying Wu, Yi-Chun Yeh, Yu-Chih Yang, Ching Chou, Ming-Tsan Liu, Ho-Sheng Wu, Jia-Tsrong Chan, Pei-Wen Hsiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2842297?pdf=render