Novel Approaches for the Solid-Phase Synthesis of Dihydroquinazoline-2(1<i>H</i>)-One Derivatives and Biological Evaluation as Potential Anticancer Agents
In the design of antineoplastic drugs, quinazolinone derivatives are often used as small molecule inhibitors for kinases or receptor kinases, such as the EGFR tyrosine kinase inhibitor gefitinib, p38MAP kinase inhibitor <b>DQO-501</b>, and BRD4 protein inhibitor <b>PFI-1</b>....
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-12-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/23/8577 |