The Formation of Glycan-Specific Natural Antibodies Repertoire in GalT-KO Mice Is Determined by Gut Microbiota

The Formation of Glycan-Specific Natural Antibodies Repertoire in GalT-KO Mice Is Determined by Gut Microbiota

Gut commensal bacteria are known to have a significant role in regulating the innate and adaptive immune homeostasis. Alterations in the intestinal microbial composition have been associated with several disease states, including autoimmune and inflammatory conditions. However, it is not entirely cl...

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Bibliographic Details
Main Authors: Daniel Bello-Gil, Christophe Audebert, Sara Olivera-Ardid, Magdiel Pérez-Cruz, Gaël Even, Nailya Khasbiullina, Nausicaa Gantois, Nadezhda Shilova, Sophie Merlin, Cristina Costa, Nicolai Bovin, Rafael Mañez
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
GalT-KO mice
gut microbiota
metagenetic high-throughput sequencing
16S rRNA gene
natural anti-glycan antibodies
printed glycan array
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00342/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00342/full

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