A New HIV-1 K28E32-Reverse Transcriptase Variant Associated with the Rapid Expansion of CRF07_BC among Men Who Have Sex with Men

A New HIV-1 K28E32-Reverse Transcriptase Variant Associated with the Rapid Expansion of CRF07_BC among Men Who Have Sex with Men

ABSTRACT HIV-1 CRF07_BC originated among injection drug users (IDUs) in China. After diffusing into men who have sex with men (MSM), CRF07_BC has shown a rapid expansion in this group; however, the mechanism remains unclear. Here, we identified a new K28E32 variant of CRF07_BC that was characterized...

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Bibliographic Details
Main Authors: Jingwan Han, Yan-Heng Zhou, Yingying Ma, Guoxin Zhu, Dong Zhang, Bo Zhu, Tong Cheng, Lanfeng Wang, Jian-Hua Wang, Lin Li, Chiyu Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
HIV-1
CRF07_BC
variant
reverse transcriptase
men who have sex with men
replication ability
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02545-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02545-22

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