Brain signal complexity in adults with Down syndrome: Potential application in the detection of mild cognitive impairment

BackgroundDown syndrome (DS) is considered the most frequent cause of early-onset Alzheimer’s disease (AD), and the typical pathophysiological signs are present in almost all individuals with DS by the age of 40. Despite of this evidence, the investigation on the pre-dementia stages in DS is scarce....

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Main Authors: Alberto Fernández, Federico Ramírez-Toraño, Ricardo Bruña, Pilar Zuluaga, Susanna Esteba-Castillo, Daniel Abásolo, Fernando Moldenhauer, Elizabeth Shumbayawonda, Fernando Maestú, Javier García-Alba
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Aging Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.988540/full