Novel [18F]-labeled thiol for the labeling of Dha- or maleimide-containing biomolecules

Abstract Background Prosthetic approach for the radiolabeling of biologics with fluorine-18 is a robust strategy and has been employed for many years. It requires fast, biocompatible and selective reactions suited to these fragile molecules. Michael addition of a nucleophilic thiol moiety on α,β-uns...

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Bibliografiska uppgifter
Huvudupphovsmän: Mylène Richard, Françoise Hinnen, Bertrand Kuhnast
Materialtyp: Artikel
Språk:English
Publicerad: SpringerOpen 2022-04-01
Serie:EJNMMI Radiopharmacy and Chemistry
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Länkar:https://doi.org/10.1186/s41181-022-00160-5