Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains

Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains

Inside the female genital tract, mammalian sperm undergo a maturation process called capacitation, which primes the sperm to navigate across the oviduct and fertilize the egg. Sperm capacitation and motility are controlled by 3′,5′-cyclic adenosine monophosphate (cAMP). Here, we...

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Bibliographic Details
Main Authors: Diana N. Raju, Jan N. Hansen, Sebastian Rassmann, Birthe Stüven, Jan F. Jikeli, Timo Strünker, Heinz G. Körschen, Andreas Möglich, Dagmar Wachten
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
cilia
flagella
optogenetics
cAMP
beat pattern
motility
navigation
sperm
Online Access:https://www.mdpi.com/2073-4409/8/7/648

Internet

https://www.mdpi.com/2073-4409/8/7/648

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