mTOR complexes differentially orchestrates eosinophil development in allergy

Abstract Eosinophil infiltration is considered a hallmark in allergic airway inflammation, and the blockade of eosinophil differentiation may be an effective approach for treating eosinophil-related disorders. Mammalian target of rapamycin (mTOR) is a vital modulator in cell growth control and relat...

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Bibliographic Details
Main Authors: Chen Zhu, Lixia Xia, Fei Li, Lingren Zhou, Qingyu Weng, Zhouyang Li, Yinfang Wu, Yuanyuan Mao, Chao Zhang, Yanping Wu, Miao Li, Songmin Ying, Zhihua Chen, Huahao Shen, Wen Li
Format: Article
Language:English
Published: Nature Portfolio 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25358-z