An accurate prediction model of digenic interaction for estimating pathogenic gene pairs of human diseases

Increasing evidence shows that genetic interaction across the entire genome may explain a non-trivial fraction of genetic diseases. Digenic interaction is the simplest manifestation of genetic interaction among genes. However, systematic exploration of digenic interactive effects on the whole genome...

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Bibliographic Details
Main Authors: Yangyang Yuan, Liubin Zhang, Qihan Long, Hui Jiang, Miaoxin Li
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002914