Identification of SARS-CoV-2 Receptor Binding Inhibitors by In Vitro Screening of Drug Libraries

Identification of SARS-CoV-2 Receptor Binding Inhibitors by In Vitro Screening of Drug Libraries

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) global pandemic. The first step of viral infection is cell attachment, which is mediated by the binding of the SARS-CoV-2 receptor binding domain (RBD), part of the virus spike pro...

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Bibliographic Details
Main Authors: Alon Ben David, Eran Diamant, Eyal Dor, Ada Barnea, Niva Natan, Lilach Levin, Shira Chapman, Lilach Cherry Mimran, Eyal Epstein, Ran Zichel, Amram Torgeman
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
SARS-CoV-2
COVID-19
drug repurposing
spike protein
receptor binding domain (RBD)
angiotensin-converting enzyme 2 (ACE2), high-throughput screening
Online Access:https://www.mdpi.com/1420-3049/26/11/3213

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https://www.mdpi.com/1420-3049/26/11/3213

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