Multivalent MVA-vectored vaccine elicits EBV neutralizing antibodies in rhesus macaques that reduce EBV infection in humanized mice

Multivalent MVA-vectored vaccine elicits EBV neutralizing antibodies in rhesus macaques that reduce EBV infection in humanized mice

IntroductionEpstein-Barr virus (EBV) is an oncogenic human herpesvirus associated with ~350,000 cases of lymphoid and epithelial malignancies every year, and is etiologically linked to infectious mononucleosis and multiple sclerosis. Despite four decades of research, no EBV vaccine candidate has yet...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Gabriela M. Escalante, Ivana G. Reidel, Lorraine Z. Mutsvunguma, Simeon Cua, Brenda A. Tello, Esther Rodriguez, Mafalda A. Farelo, Cloe Zimmerman, Murali Muniraju, He Li, Aparna N. Govindan, Michael K. Axthelm, Scott W. Wong, Javier Gordon Ogembo
Format: Artykuł
Język:English
Wydane: Frontiers Media S.A. 2024-09-01
Seria:Frontiers in Immunology
Hasła przedmiotowe:
Epstein-Barr virus
infectious mononucleosis
cancer
prophylactic vaccine
glycoprotein
neutralizing antibody
Dostęp online:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1445209/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1445209/full

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