Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil’s Antimicrobial Response by Engaging the Histamine 2 Receptor

We found that histamine (10−9 M) did not have any effect on the in vitro capture of Escherichia coli by neutrophils but accelerated its intracellular killing. In contrast, histamine (10−6 M) delayed the capture of Escherichia coli by neutrophils and reduced the amounts of pHrodo zymosan particles in...

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Bibliographic Details
Main Authors: Karim Dib, Amal El Banna, Clara Radulescu, Guillermo Lopez Campos, Gerard Sheehan, Kevin Kavanagh
Format: Article
Language:English
Published: Karger Publishers 2022-07-01
Series:Journal of Innate Immunity
Subjects:
Online Access:https://beta.karger.com/Article/FullText/525536