Transient co-expression with three O-glycosylation enzymes allows production of GalNAc-O-glycosylated Granulocyte-Colony Stimulating Factor in N. benthamiana

Transient co-expression with three O-glycosylation enzymes allows production of GalNAc-O-glycosylated Granulocyte-Colony Stimulating Factor in N. benthamiana

Abstract Background Expression of economically relevant proteins in alternative expression platforms, especially plant expression platforms, has gained significant interest in recent years. A special interest in working with plants as bioreactors for the production of pharmaceutical proteins is rela...

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Bibliographic Details
Main Authors: Israel A. Ramírez-Alanis, Justin B. Renaud, Silverio García-Lara, Rima Menassa, Guy A. Cardineau
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Plant Methods
Subjects:
Mucin-type O-glycosylation
G-CSF
Granulocyte-Colony Stimulating Factor
Nicotiana benthamiana
Pharmaceutical glycoprotein
Molecular farming
Online Access:http://link.springer.com/article/10.1186/s13007-018-0363-y

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http://link.springer.com/article/10.1186/s13007-018-0363-y

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