Targeting Ezh2 could overcome docetaxel resistance in prostate cancer cells

Abstract Background Docetaxel was used to treat metastatic CRPC patients. However, Doc resistance in prostate cancer (PCa) hinders its clinical application. Objective To understand the underlying mechanisms by which Doc resistance is developed and to find novel therapeutic target to cure Doc resista...

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Bibliographic Details
Main Authors: Xiaofu Qiu, Wei Wang, Bijun Li, Bo Cheng, Kangjian Lin, Jian Bai, Huanhui Li, Guosheng Yang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-5228-2