The alleviation of lipid deposition in steatosis hepatocytes by capsaicin-loaded α-lactalbumin nanomicelles via promoted endocytosis and synergetic multiple signaling pathways

A capsaicin delivery system was developed by self-assembling of α-lactalbumin polypeptides into nanomicelles. The capsaicin was loaded into the α-lactalbumin micelles via hydrophobic interaction with an embedding amount of 126.58 mg/g. Steatotic HepG2 cells were treated with the capsaicin-loaded nan...

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Bibliographic Details
Main Authors: Congcong Zuo, Huijuan Zhang, Shuang Liang, Wendi Teng, Cheng Bao, Dan Li, Yuling Hu, Qimeng Wang, Zekun Li, Yuan Li
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621000451