The alleviation of lipid deposition in steatosis hepatocytes by capsaicin-loaded α-lactalbumin nanomicelles via promoted endocytosis and synergetic multiple signaling pathways
A capsaicin delivery system was developed by self-assembling of α-lactalbumin polypeptides into nanomicelles. The capsaicin was loaded into the α-lactalbumin micelles via hydrophobic interaction with an embedding amount of 126.58 mg/g. Steatotic HepG2 cells were treated with the capsaicin-loaded nan...
Main Authors: | Congcong Zuo, Huijuan Zhang, Shuang Liang, Wendi Teng, Cheng Bao, Dan Li, Yuling Hu, Qimeng Wang, Zekun Li, Yuan Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-04-01
|
Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464621000451 |
Similar Items
-
Effects of Capsaicin on Glucose Uptake and Consumption in Hepatocytes
by: Haolong Zeng, et al.
Published: (2023-07-01) -
Piceatannol attenuates fat accumulation and oxidative stress in steatosis-induced HepG2 cells
by: Jason Szuhao Yang, et al.
Published: (2020-11-01) -
Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice
by: Chian-Jiun Liou, et al.
Published: (2020-09-01) -
Synergistic Effects of the Aerobic Training and Capsaicin on the Expression level of AMP-Activated Protein Kinase and Protein Kinase B Gene of Liver Tissue in Rat Fed a High-Fat Diet
by: Ghasem Torabi Palat Kaleh, et al.
Published: (2022-03-01) -
An overview of bovine α-lactalbumin structure and functionality
by: Nicoleta STĂNCIUC, et al.
Published: (2010-12-01)