Self-DNA Exposure Induces Developmental Defects and Germline DNA Damage Response in <i>Caenorhabditis elegans</i>

Self-DNA Exposure Induces Developmental Defects and Germline DNA Damage Response in <i>Caenorhabditis elegans</i>

All organisms, from bacteria to mammals, sense and respond to foreign nucleic acids to fight infections in order to survive and preserve genome integrity across generations. The innate immune system is an evolutionarily conserved defence strategy. Complex organisms have developed various cellular pr...

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Bibliographic Details
Main Authors: Marcello Germoglio, Adele Adamo, Guido Incerti, Fabrizio Cartenì, Silvia Gigliotti, Aurora Storlazzi, Stefano Mazzoleni
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biology
Subjects:
<i>Caenorhabditis elegans</i>
self-DNA
germline
apoptosis
nematode
Online Access:https://www.mdpi.com/2079-7737/11/2/262

Internet

https://www.mdpi.com/2079-7737/11/2/262

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