Jump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug Transporter.

ABCG2/BCRP is a membrane protein, involved in xenobiotic and endobiotic transport in key pharmacological barriers and drug metabolizing organs, in the protection of stem cells, and in multidrug resistance of cancer. Pharmacogenetic studies implicated the role of ABCG2 in response to widely used medi...

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Bibliographic Details
Main Authors: Laura László, Balázs Sarkadi, Tamás Hegedűs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5065228?pdf=render