Microvesicle shedding and lysosomal repair fulfill divergent cellular needs during the repair of streptolysin O-induced plasmalemmal damage.

Microvesicle shedding and lysosomal repair fulfill divergent cellular needs during the repair of streptolysin O-induced plasmalemmal damage.

Pathogenic bacteria secrete pore-forming toxins that permeabilize the plasma membrane of host cells. Nucleated cells possess protective mechanisms that repair toxin-damaged plasmalemma. Currently two putative repair scenarios are debated: either the isolation of the damaged membrane regions and thei...

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Bibliographic Details
Main Authors: Alexander P Atanassoff, Heidi Wolfmeier, Roman Schoenauer, Andrea Hostettler, Avi Ring, Annette Draeger, Eduard B Babiychuk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089743&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089743&type=printable

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