Autophagy-Associated IL-15 Production Is Involved in the Pathogenesis of Leprosy Type 1 Reaction

Autophagy-Associated IL-15 Production Is Involved in the Pathogenesis of Leprosy Type 1 Reaction

Leprosy reactional episodes are acute inflammatory events that may occur during the clinical course of the disease. Type 1 reaction (T1R) is associated with an increase in neural damage, and the understanding of the molecular pathways related to T1R onset is pivotal for the development of strategies...

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Bibliographic Details
Main Authors: Bruno Jorge de Andrade Silva, Tamiris Lameira Bittencourt, Thyago Leal-Calvo, Mayara Abud Mendes, Rhana Berto da Silva Prata, Mayara Garcia de Mattos Barbosa, Priscila Ribeiro Andrade, Suzana Côrte-Real, Gilberto Marcelo Sperandio da Silva, Milton Ozório Moraes, Euzenir Nunes Sarno, Roberta Olmo Pinheiro
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
autophagy
<i>Mycobacterium leprae</i>
leprosy or T1R
macrophage or THP-1
phagosome
lysosomes
Online Access:https://www.mdpi.com/2073-4409/10/9/2215

Internet

https://www.mdpi.com/2073-4409/10/9/2215

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