Sibship size, birth order and risk of asthma and allergy: protocol for a systematic review and meta-analysis

Introduction The hygiene hypothesis suggests that reduced exposure to microbes might have contributed to the increase in prevalence and incidence of asthma and allergy observed during the second half of the last century. Following this proposal, several studies have investigated the role of sibship...

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Main Authors: Göran Wennergren, Bright I Nwaru, Emma Goksör, Daniil Lisik, Athina Ioannidou, Gregorio Milani, Sungkutu Nyassi, Saliha Selin Özuygur Ermis, Giulia C I Spolidoro
Format: Article
Language:English
Published: BMJ Publishing Group 2021-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/8/e045795.full