Development and pre-clinical evaluation of two LAIV strains against potentially pandemic H2N2 influenza virus.

H2N2 Influenza A caused the Asian flu pandemic in 1957, circulated for more than 10 years and disappeared from the human population after 1968. Given that people born after 1968 are naïve to H2N2, that the virus still circulates in wild birds and that this influenza subtype has a proven pandemic tra...

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Bibliographic Details
Main Authors: Irina Isakova-Sivak, Jørgen de Jonge, Tatiana Smolonogina, Andrey Rekstin, Geert van Amerongen, Harry van Dijken, Justin Mouthaan, Paul Roholl, Victoria Kuznetsova, Elena Doroshenko, Vadim Tsvetnitsky, Larisa Rudenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25058039/?tool=EBI