AGENTES ANTINEOPLÁSICOS BIORREDUTÍVEIS: AVANÇOS E DESAFIOS APÓS 20 ANOS

AGENTES ANTINEOPLÁSICOS BIORREDUTÍVEIS: AVANÇOS E DESAFIOS APÓS 20 ANOS

Solid tumors are frequently affected by the presence of hypoxic cells, originating anomalous and disordered cell growth. This subpopulation presents resistance to conventional chemotherapy agents and radiotherapy, due to the difficulties of reaching the target region, the permanence in the G0 phase...

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Bibliographic Details
Main Authors: Pedro A. L. Santana, Gabriel V. L. Marques, Mariana F. P. Cortezzi, Ricardo J. Alves, Renata B. de Oliveira
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2024-03-01
Series:Química Nova
Subjects:
solid tumor
bioreductive prodrugs
hypoxic cells
hypoxia activated prodrugs.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422024000300300&lng=pt&tlng=pt

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422024000300300&lng=pt&tlng=pt

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